Read through the following passage and then decide which words should be placed in the gaps.  
a  Enzymes are globular proteins which act as biological catalysts. They are able to temporarily bind with substrate molecules due to an region know as the_____________________. Because enzymes are proteins their activity can be affected by pH and ___________________. The catalytic ability of enzymes depends on their three dimensional shape, this is more commonly refered to as the enzymes __________ structure. During an enzyme catalysed reaction a transition occurs during which the reactants are referred to as the ______________________.  



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